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Obicetrapib

Chemical Structure Obicetrapib

CAS No.: 866399-87-3

Obicetrapib( AMG-899;AMG899;TA-8995;DEX-001)

Catalog No.GY05564Research Only, Not for Human Use!

Obicetrapib (AMG-899, TA-8995, DEX-001) is a potent, ora cholesteryl ester transfer protein (CETP) inhibitor for treatment of dyslipidaemia

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Purity & Documentation Purity: > 98%(HPLC) Select Batch:

Biological Activity

Obicetrapib (AMG-899, TA-8995, DEX-001) is a potent, ora cholesteryl ester transfer protein (CETP) inhibitor for treatment of dyslipidaemia.

Physicochemical Properties

M.Wt 722.609
Formula C32H31F9N4O5
CAS No. 866399-87-3
Storage
Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 3 Month
Shipping
Solubility

Chemical Name 4-[2-[[3,5-bis(trifluoromethyl)phenyl]methyl-[(2R,4S)-1-ethoxycarbonyl-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinolin-4-yl]amino]pyrimidin-5-yl]oxybutanoic acid

Clinical Information

Dyslipidemia
Phase 2 Clinical

References

1. Ford J, et al. Br J Clin Pharmacol. 2014 Sep;78(3):498-508.

2. Hovingh GK, et al. Lancet. 2015 Aug 1;386(9992):452-60.

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