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You are here:Home-Inhibitors & Agonists-Others-AP2-associated Kinase 1 (AAK1)-BMT-046091
BMT-046091

Chemical Structure BMT-046091

CAS No.: 1551401-20-7

BMT-046091(BMT046091)

Catalog No.GY05500Research Only, Not for Human Use!

BMT-046091 (BMT046091) is a potent and selective AAK1 inhibitor with IC50 of 2

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Purity & Documentation Purity: > 98%(HPLC) Select Batch:

Biological Activity

BMT-046091 (BMT046091) is a potent and selective AAK1 inhibitor with IC50 of 2.8 nM; BMT-046091 is inactive in a panel of functional or binding assays for receptors, transporters and enzymes at >5 μM; [3H]BMT-046091 is a potent and selective radioligand to determine AAK1 distribution and target engagement.

Physicochemical Properties

M.Wt 311.385
Formula C18H21N3O2
CAS No. 1551401-20-7
Storage
Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 3 Month
Shipping
Solubility

Chemical Name (S)-8-((2-amino-4-methylpentyl)oxy)benzo[c][2,7]naphthyridin-5(6H)-one

Clinical Information


References

1. Louis JV, et al. Neuropharmacology. 2017 May 15;118:167-174.

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