c-Fos/AP-1|Inhibitors Agonists Modulators Antagonists|RayStarBio.com

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Cat. No.	Product Name	CAS No.	Information
GY04209	T-5224	530141-72-1	T-5224 is a small molecule inhibitor of c-Fos/AP-1 that specifically inhibits the binding of AP-1 to the AP-1 binding site of the promoter region, attenuates the gelatinase activity of MMP-2 and -9; inhibits the mRNA expression levels of MMP-1, 3, and 13, and IL-1β, TNF-α and IL-6 in IL-1-stimulated human chondrocytes, significantly inhibits the invasion, migration, and MMP activity of HNSCC cells, prevents lymph node metastasis in an oral cancer model; decreases the release of collagen selectively in SSc fibroblasts, prevents dermal fibrosis in vivo.