PROTAC Linkers|Inhibitors Agonists Modulators Antagonists|RayStarBio.com

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The PROTAC linker connects two moieties: a small peptide residue for E3 ubiquitin ligase recognition,and a ligand that can be recognized by a targeted protein.

Unlike the small molecule ligands, the length of the linker has been randomly selected for PROTACs, varying from 12-carbon to over 20-carbon in length. An optimal linker will allow for maximal interaction between the two moieties (target protein and E3 ligase) resulting in efficient ubiquitination of the target protein and its ultimate degradation.

Cat. No.	Product Name	CAS No.	Information
GY07103	Bis-PEG6-acid	77855-76-6	A PEG linker for PROTAC.
GY07102	Bis-PEG5-acid	77855-75-5	A PEG linker for PROTAC.
GY07101	Bis-PEG4-acid	32775-08-9	A PEG linker for PROTAC.
GY07098	N3-PEG2-CH2COOH	882518-90-3	A PEG2 linker for PROTAC.
GY07097	N3-PEG4-CH2COOH	201467-81-4	A PEG4 linker for PROTAC.
GY07092	N3-PEG3-CH2COOH	172531-37-2	A PEG3 linker for PROTAC.

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