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Request The Product List ofFungal Infection Fungal Infection

    Fungal infection, also known as a mycosis, refers to the invasion of a host's tissue by specific types of fungi. Mycoses often start in the lungs following inhalation of fungal spores or on the skin due to localized colonization.

Cat. No. Product Name CAS No. Information
GY06076

SCY-078

1207753-03-4

SCY-078 (MK-3118;MK 3118;SCY 078) is a novel orally bioavailable fungal beta-1,3-D glucan synthetase inhibitor against Candida species C. glabrata (MIC 0.03 to 0.25 ug/ml), C. parapsilosis (MIC 0.06 to 0.25 ug/ml); shows actvity in an in vivo neutropenic murine model.

GY06053

VT-1161

1340593-59-0

VT-1161(VT1161) is a potent, highly-selective, and oral fungal CYP51 inhibitor with Kd of ≤ 39 nM; demonstrates >2,000-fold selectivit over human CYP51, weakly inhibits human CYP2C9, CYP2C19, and CYP3A4; exhibits excellent potency against key yeast and dermatophyte strains.

GY06040

Voriconazole

137234-62-9

Voriconazole (UK-109496;UK109496;UK 109496) is a triazole antifungal agent that acts as a 14α-demethylase inhibitor; used to treat and prevent invasive fungal infections including aspergillosis andcandidiasis and fungal infections caused by Scedosporium and Fusarium species.

GY05960

Fosfluconazole

194798-83-9

Fosfluconazole is a water-soluble, phosphate prodrug of fluconazole, a triazole antifungal agent and 14-alpha demethylase inhibitor used in the treatment and prevention of superficial and systemic fungal infections.

GY05859

Butenafine hydrochloride

101827-46-7

Butenafine hydrochloride is a synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase; displays superior activity against Candida albicans than terbinafine and naftifine; demonstrates low MICs against Cryptococcus and Aspergillus.

GY05838

Posaconazole hydrate

1198769-38-8

Posaconazole hydrate (SCH-56592 hydrate) is a triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors, more potent at inhibiting 14α-demethylase than itraconazole.

GY05813

Nystatin

1400-61-9

A polyene antifungal antibiotic that works by disrupting the cell membrane of the fungal cells.

GY05791

Posaconazole

171228-49-2

Posaconazole (SCH-56592) is a triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors, more potent at inhibiting 14α-demethylase than itraconazole.

GY05785

Caspofungin acetate

179463-17-3

Caspofungin acetate (L-743872;L-743873;MK-0991) is a lipopeptide antifungal agent that works by inhibiting the enzyme 1,3-beta-glucan synthase and thereby disturbing the integrity of the fungal cell wall.

GY05780

F-901318

1928707-56-5

F-901318 (Olorofim;F 901318) is a novel antifungal agent that inhibits A. fumigatus DHODH with IC50 of 44 nM; shows little inhibition of human DHODH (>100 uM); displays excellent potency against a broad range of pathogenic filamentous and dimorphic fungi, including Penicillium spp., Coccidiodes immitis, H. capsulatum, Blastomyces dermatitidis, Fusarium spp., and the difficult-to-treat Scedosporium spp.

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