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WAY-262611 (WAY262611) is a potent, orally active and Wnt/β-catenin pathway agonist with EC50 of 0.63 nM, via inhibition of dickkopf-1 (DKK-1); increases bone formation rate in ovariectomized rats; inhibits cell migration of fibroblast-like synoviocytes (FLSs) in rheumatoid arthritis.

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